Long-term potentiation at pyramidal cell to somatostatin interneuron synapses controls hippocampal network plasticity and memory

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Hippocampal somatostatin (SOM) cells are dendrite-projecting inhibitory interneurons. CA1 SOM cells receive major excitatory inputs from pyramidal cells (PC-SOM synapses) which show mGluR1a- and mTORC1-mediated long-term potentiation (LTP). PC-SOM synapse LTP contributes to CA1 network metaplasticit...

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Detalles Bibliográficos
Autores principales: Asgarihafshejani, Azam, Honoré, Ève, Michon, François-Xavier, Laplante, Isabel, Lacaille, Jean-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062215/
https://www.ncbi.nlm.nih.gov/pubmed/35521524
http://dx.doi.org/10.1016/j.isci.2022.104259
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