Utility of the DHFR-based destabilizing domain across mouse models of retinal degeneration and aging

The Escherichia coli dihydrofolate reductase (DHFR) destabilizing domain (DD) serves as a promising approach to conditionally regulate protein abundance in a variety of tissues. To test whether this approach could be effectively applied to a wide variety of aged and disease-related ocular mouse mode...

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Detalles Bibliográficos
Autores principales: Peng, Hui, Ramadurgum, Prerana, Woodard, DaNae R., Daniel, Steffi, Nakahara, Emi, Renwick, Marian, Aredo, Bogale, Datta, Shyamtanu, Chen, Bo, Ufret-Vincenty, Rafael, Hulleman, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062244/
https://www.ncbi.nlm.nih.gov/pubmed/35521529
http://dx.doi.org/10.1016/j.isci.2022.104206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062244/
https://www.ncbi.nlm.nih.gov/pubmed/35521529
http://dx.doi.org/10.1016/j.isci.2022.104206

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