Protein folding stabilities are a major determinant of oxidation rates for buried methionine residues

The oxidation of protein-bound methionines to form methionine sulfoxides has a broad range of biological ramifications, making it important to delineate factors that influence methionine oxidation rates within a given protein. This is especially important for biopharmaceuticals, where oxidation can...

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Detalles Bibliográficos
Autores principales: Walker, Ethan J., Bettinger, John Q., Welle, Kevin A., Hryhorenko, Jennifer R., Molina Vargas, Adrian M., O’Connell, Mitchell R., Ghaemmaghami, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062257/
https://www.ncbi.nlm.nih.gov/pubmed/35346688
http://dx.doi.org/10.1016/j.jbc.2022.101872

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