Powerful eQTL mapping through low-coverage RNA sequencing

Mapping genetic variants that regulate gene expression (eQTL mapping) in large-scale RNA sequencing (RNA-seq) studies is often employed to understand functional consequences of regulatory variants. However, the high cost of RNA-seq limits sample size, sequencing depth, and, therefore, discovery powe...

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Detalles Bibliográficos
Autores principales: Schwarz, Tommer, Boltz, Toni, Hou, Kangcheng, Bot, Merel, Duan, Chenda, Loohuis, Loes Olde, Boks, Marco P., Kahn, René S., Ophoff, Roel A., Pasaniuc, Bogdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062329/
https://www.ncbi.nlm.nih.gov/pubmed/35519825
http://dx.doi.org/10.1016/j.xhgg.2022.100103

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