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Discovery of methylpyrimidine ring-fused diterpenoid analogs as a novel testosterone synthesis promoter
Herein we screened our small synthetic library of diterpenoid analogs for hit compounds on promoting testosterone synthesis and the methylpyrimidine ring-fused diterpenoid analog 7 was obtained as the hit. Based on the hit, a series of derivatives were designed, synthesized and evaluated for their e...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062398/ https://www.ncbi.nlm.nih.gov/pubmed/35520707 http://dx.doi.org/10.1039/c9ra00702d |