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Identification of a poly-cyclopropylglycine–containing peptide via bioinformatic mapping of radical S-adenosylmethionine enzymes

Peptide-derived natural products are a large class of bioactive molecules that often contain chemically challenging modifications. In the biosynthesis of ribosomally synthesized and posttranslationally modified peptides (RiPPs), radical-SAM (rSAM) enzymes have been shown to catalyze the formation of...

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Detalles Bibliográficos
Autores principales:	Kostenko, Anastasiia, Lien, Yi, Mendauletova, Aigera, Ngendahimana, Thacien, Novitskiy, Ivan M., Eaton, Sandra S., Latham, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062424/ https://www.ncbi.nlm.nih.gov/pubmed/35367210 http://dx.doi.org/10.1016/j.jbc.2022.101881

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