Deciphering functional redundancy and energetics of malate oxidation in mycobacteria

Oxidation of malate to oxaloacetate, catalyzed by either malate dehydrogenase (Mdh) or malate quinone oxidoreductase (Mqo), is a critical step of the tricarboxylic acid cycle. Both Mqo and Mdh are found in most bacterial genomes, but the level of functional redundancy between these enzymes remains u...

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Detalles Bibliográficos
Autores principales: Harold, Liam K., Jinich, Adrian, Hards, Kiel, Cordeiro, Alexandra, Keighley, Laura M., Cross, Alec, McNeil, Matthew B., Rhee, Kyu, Cook, Gregory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062433/
https://www.ncbi.nlm.nih.gov/pubmed/35337802
http://dx.doi.org/10.1016/j.jbc.2022.101859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062433/
https://www.ncbi.nlm.nih.gov/pubmed/35337802
http://dx.doi.org/10.1016/j.jbc.2022.101859

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