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Deciphering functional redundancy and energetics of malate oxidation in mycobacteria
Oxidation of malate to oxaloacetate, catalyzed by either malate dehydrogenase (Mdh) or malate quinone oxidoreductase (Mqo), is a critical step of the tricarboxylic acid cycle. Both Mqo and Mdh are found in most bacterial genomes, but the level of functional redundancy between these enzymes remains u...
Autores principales: | Harold, Liam K., Jinich, Adrian, Hards, Kiel, Cordeiro, Alexandra, Keighley, Laura M., Cross, Alec, McNeil, Matthew B., Rhee, Kyu, Cook, Gregory M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062433/ https://www.ncbi.nlm.nih.gov/pubmed/35337802 http://dx.doi.org/10.1016/j.jbc.2022.101859 |
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