Cargando…
Antibacterial activity and mechanism of action of a thiophenyl substituted pyrimidine derivative
The issue of multidrug resistant bacteria is a worldwide health threat. To develop new antibacterial agents with new mechanisms of action is thus an urgent request to address this antibiotic resistance crisis. In the present study, a new thiophenyl-pyrimidine derivative was prepared and utilized as...
Autores principales: | Fang, Zhiyuan, Li, Yanan, Zheng, Yuanyuan, Li, Xiaomei, Lu, Yu-Jing, Yan, Siu-Cheong, Wong, Wing-Leung, Chan, Kin-Fai, Wong, Kwok-yin, Sun, Ning |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062536/ https://www.ncbi.nlm.nih.gov/pubmed/35515309 http://dx.doi.org/10.1039/c9ra01001g |
Ejemplares similares
-
Efficient Synthesis of Amine-Linked 2,4,6-Trisubstituted
Pyrimidines as a New Class
of Bacterial FtsZ Inhibitors
por: Chan, Kin-Fai, et al.
Publicado: (2017) -
The Suzuki Reaction Applied to the Synthesis of Novel Pyrrolyl and Thiophenyl Indazoles
por: Migliorini, Antonella, et al.
Publicado: (2012) -
Rational Design of Berberine-Based FtsZ Inhibitors with Broad-Spectrum Antibacterial Activity
por: Sun, Ning, et al.
Publicado: (2014) -
Rational structural modification of the isatin scaffold to develop new and potent antimicrobial agents targeting bacterial peptidoglycan glycosyltransferase
por: Wang, Yong, et al.
Publicado: (2021) -
Microwave Assisted Synthesis, Pharmacological Activities, and Molecular Docking Studies of Ethyl 2-[2-Substituted-4-(Thiophenyl) Thiazolyl] Acetates
por: Attimarad, Mahesh Veerabhadra, et al.
Publicado: (2017)