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Case Report: Esthesioneuroblastoma Involving the Optic Pathways

Olfactory neuroblastoma, or esthesioneuroblastoma, is an uncommon malignant tumor originating from the neural crest that commonly occurs in the upper nasal cavity. Its ectopic origin is extremely rare, especially when located in the optical pathways. This paper reports the case of a giant ectopic es...

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Autores principales: da Silva, Vithor Ely B., Buniatti, Samuel R., Costa, Felipe D'Almeida, Torrecillas, Mauricio R., de Oliveira, Jean G., Rassi, Marcio S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062615/
https://www.ncbi.nlm.nih.gov/pubmed/35521435
http://dx.doi.org/10.3389/fsurg.2022.875881
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author da Silva, Vithor Ely B.
Buniatti, Samuel R.
Costa, Felipe D'Almeida
Torrecillas, Mauricio R.
de Oliveira, Jean G.
Rassi, Marcio S.
author_facet da Silva, Vithor Ely B.
Buniatti, Samuel R.
Costa, Felipe D'Almeida
Torrecillas, Mauricio R.
de Oliveira, Jean G.
Rassi, Marcio S.
author_sort da Silva, Vithor Ely B.
collection PubMed
description Olfactory neuroblastoma, or esthesioneuroblastoma, is an uncommon malignant tumor originating from the neural crest that commonly occurs in the upper nasal cavity. Its ectopic origin is extremely rare, especially when located in the optical pathways. This paper reports the case of a giant ectopic esthesioneuroblastoma of the optic pathways that were surgically treated through a cranio-orbital-zygomatic (COZ) craniotomy with extensive resection, in addition to a literature review. The patient is a 46-year-old female presenting with a 4-month history of visual loss in the left eye. Since she was previously blind in the right eye from a traumatic injury, it was evolving to loss of bilateral vision. Imaging depicted an expansive infiltrating lesion involving the entire path of the right optic nerve, extending to the optic chiasm, cisternal portion of the left optic nerve, bilateral optic tract, and hypothalamus. Investigation of pituitary function was unremarkable. Esthesioneuroblastoma is a rare tumor with poorly defined standard clinical management. Its ectopic presentation makes the diagnosis even more challenging, making it difficult to manage these cases properly. Surgeons should be aware of this rare possibility, as early aggressive treatment is likely to be associated with better results.
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spelling pubmed-90626152022-05-04 Case Report: Esthesioneuroblastoma Involving the Optic Pathways da Silva, Vithor Ely B. Buniatti, Samuel R. Costa, Felipe D'Almeida Torrecillas, Mauricio R. de Oliveira, Jean G. Rassi, Marcio S. Front Surg Surgery Olfactory neuroblastoma, or esthesioneuroblastoma, is an uncommon malignant tumor originating from the neural crest that commonly occurs in the upper nasal cavity. Its ectopic origin is extremely rare, especially when located in the optical pathways. This paper reports the case of a giant ectopic esthesioneuroblastoma of the optic pathways that were surgically treated through a cranio-orbital-zygomatic (COZ) craniotomy with extensive resection, in addition to a literature review. The patient is a 46-year-old female presenting with a 4-month history of visual loss in the left eye. Since she was previously blind in the right eye from a traumatic injury, it was evolving to loss of bilateral vision. Imaging depicted an expansive infiltrating lesion involving the entire path of the right optic nerve, extending to the optic chiasm, cisternal portion of the left optic nerve, bilateral optic tract, and hypothalamus. Investigation of pituitary function was unremarkable. Esthesioneuroblastoma is a rare tumor with poorly defined standard clinical management. Its ectopic presentation makes the diagnosis even more challenging, making it difficult to manage these cases properly. Surgeons should be aware of this rare possibility, as early aggressive treatment is likely to be associated with better results. Frontiers Media S.A. 2022-04-19 /pmc/articles/PMC9062615/ /pubmed/35521435 http://dx.doi.org/10.3389/fsurg.2022.875881 Text en Copyright © 2022 da Silva, Buniatti, Costa, Torrecillas, de Oliveira and Rassi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
da Silva, Vithor Ely B.
Buniatti, Samuel R.
Costa, Felipe D'Almeida
Torrecillas, Mauricio R.
de Oliveira, Jean G.
Rassi, Marcio S.
Case Report: Esthesioneuroblastoma Involving the Optic Pathways
title Case Report: Esthesioneuroblastoma Involving the Optic Pathways
title_full Case Report: Esthesioneuroblastoma Involving the Optic Pathways
title_fullStr Case Report: Esthesioneuroblastoma Involving the Optic Pathways
title_full_unstemmed Case Report: Esthesioneuroblastoma Involving the Optic Pathways
title_short Case Report: Esthesioneuroblastoma Involving the Optic Pathways
title_sort case report: esthesioneuroblastoma involving the optic pathways
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062615/
https://www.ncbi.nlm.nih.gov/pubmed/35521435
http://dx.doi.org/10.3389/fsurg.2022.875881
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