Sesquiterpenes from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346

Two new sesquiterpenes, trichocitrinovirenes A (1) and B (2), and five known compounds including four structurally related sesquiterpenes and one γ-lactone were isolated from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346. The structures were identified by analysis of their spectrosco...

Descripción completa

Detalles Bibliográficos
Autores principales: Yaosanit, Wiriya, Rukachaisirikul, Vatcharin, Phongpaichit, Souwalak, Preedanon, Sita, Sakayaroj, Jariya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062651/
https://www.ncbi.nlm.nih.gov/pubmed/35558648
http://dx.doi.org/10.3762/bjoc.18.50
Descripción
Sumario:Two new sesquiterpenes, trichocitrinovirenes A (1) and B (2), and five known compounds including four structurally related sesquiterpenes and one γ-lactone were isolated from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346. The structures were identified by analysis of their spectroscopic data. The relative configuration was assigned based on NOEDIFF data. The absolute configuration of compound 1 was established according to specific rotations and ECD data while that of compound 2 was proposed based on biosynthetic considerations. Compound 2 possesses a rare bicyclic sesquiterpene skeleton. The antimicrobial and cytotoxic activities of the isolated compounds were evaluated.

Ejemplares similares