Sesquiterpenes from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346

Two new sesquiterpenes, trichocitrinovirenes A (1) and B (2), and five known compounds including four structurally related sesquiterpenes and one γ-lactone were isolated from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346. The structures were identified by analysis of their spectrosco...

Descripción completa

Detalles Bibliográficos
Autores principales: Yaosanit, Wiriya, Rukachaisirikul, Vatcharin, Phongpaichit, Souwalak, Preedanon, Sita, Sakayaroj, Jariya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062651/
https://www.ncbi.nlm.nih.gov/pubmed/35558648
http://dx.doi.org/10.3762/bjoc.18.50
_version_ 1784698993279762432
author Yaosanit, Wiriya
Rukachaisirikul, Vatcharin
Phongpaichit, Souwalak
Preedanon, Sita
Sakayaroj, Jariya
author_facet Yaosanit, Wiriya
Rukachaisirikul, Vatcharin
Phongpaichit, Souwalak
Preedanon, Sita
Sakayaroj, Jariya
author_sort Yaosanit, Wiriya
collection PubMed
description Two new sesquiterpenes, trichocitrinovirenes A (1) and B (2), and five known compounds including four structurally related sesquiterpenes and one γ-lactone were isolated from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346. The structures were identified by analysis of their spectroscopic data. The relative configuration was assigned based on NOEDIFF data. The absolute configuration of compound 1 was established according to specific rotations and ECD data while that of compound 2 was proposed based on biosynthetic considerations. Compound 2 possesses a rare bicyclic sesquiterpene skeleton. The antimicrobial and cytotoxic activities of the isolated compounds were evaluated.
format Online
Article
Text
id pubmed-9062651
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-90626512022-05-11 Sesquiterpenes from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346 Yaosanit, Wiriya Rukachaisirikul, Vatcharin Phongpaichit, Souwalak Preedanon, Sita Sakayaroj, Jariya Beilstein J Org Chem Full Research Paper Two new sesquiterpenes, trichocitrinovirenes A (1) and B (2), and five known compounds including four structurally related sesquiterpenes and one γ-lactone were isolated from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346. The structures were identified by analysis of their spectroscopic data. The relative configuration was assigned based on NOEDIFF data. The absolute configuration of compound 1 was established according to specific rotations and ECD data while that of compound 2 was proposed based on biosynthetic considerations. Compound 2 possesses a rare bicyclic sesquiterpene skeleton. The antimicrobial and cytotoxic activities of the isolated compounds were evaluated. Beilstein-Institut 2022-04-29 /pmc/articles/PMC9062651/ /pubmed/35558648 http://dx.doi.org/10.3762/bjoc.18.50 Text en Copyright © 2022, Yaosanit et al. https://creativecommons.org/licenses/by/4.0/This is an open access article licensed under the terms of the Beilstein-Institut Open Access License Agreement (https://www.beilstein-journals.org/bjoc/terms/terms), which is identical to the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ). The reuse of material under this license requires that the author(s), source and license are credited. Third-party material in this article could be subject to other licenses (typically indicated in the credit line), and in this case, users are required to obtain permission from the license holder to reuse the material.
spellingShingle Full Research Paper
Yaosanit, Wiriya
Rukachaisirikul, Vatcharin
Phongpaichit, Souwalak
Preedanon, Sita
Sakayaroj, Jariya
Sesquiterpenes from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346
title Sesquiterpenes from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346
title_full Sesquiterpenes from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346
title_fullStr Sesquiterpenes from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346
title_full_unstemmed Sesquiterpenes from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346
title_short Sesquiterpenes from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346
title_sort sesquiterpenes from the soil-derived fungus trichoderma citrinoviride psu-spsf346
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062651/
https://www.ncbi.nlm.nih.gov/pubmed/35558648
http://dx.doi.org/10.3762/bjoc.18.50
work_keys_str_mv AT yaosanitwiriya sesquiterpenesfromthesoilderivedfungustrichodermacitrinoviridepsuspsf346
AT rukachaisirikulvatcharin sesquiterpenesfromthesoilderivedfungustrichodermacitrinoviridepsuspsf346
AT phongpaichitsouwalak sesquiterpenesfromthesoilderivedfungustrichodermacitrinoviridepsuspsf346
AT preedanonsita sesquiterpenesfromthesoilderivedfungustrichodermacitrinoviridepsuspsf346
AT sakayarojjariya sesquiterpenesfromthesoilderivedfungustrichodermacitrinoviridepsuspsf346

Ejemplares similares