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A network model of glymphatic flow under different experimentally-motivated parametric scenarios
Flow of cerebrospinal fluid (CSF) through perivascular spaces (PVSs) in the brain delivers nutrients, clears metabolic waste, and causes edema formation. Brain-wide imaging cannot resolve PVSs, and high-resolution methods cannot access deep tissue. However, theoretical models provide valuable insigh...
Autores principales: | Tithof, Jeffrey, Boster, Kimberly A.S., Bork, Peter A.R., Nedergaard, Maiken, Thomas, John H., Kelley, Douglas H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062681/ https://www.ncbi.nlm.nih.gov/pubmed/35521514 http://dx.doi.org/10.1016/j.isci.2022.104258 |
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