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A Non-redundant Function of MNS5: A Class I α-1, 2 Mannosidase, in the Regulation of Endoplasmic Reticulum-Associated Degradation of Misfolded Glycoproteins
Endoplasmic Reticulum-Associated Degradation (ERAD) is one of the major processes in maintaining protein homeostasis. Class I α-mannosidases MNS4 and MNS5 are involved in the degradation of misfolded variants of the heavily glycosylated proteins, playing an important role for glycan-dependent ERAD i...
Autores principales: | Sun, Xiaoxia, Guo, Chenchen, Ali, Khawar, Zheng, Qian, Wei, Qiang, Zhu, Yumeng, Wang, Li, Li, Guishuang, Li, Wenjuan, Zheng, Bowen, Bai, Qunwei, Wu, Guang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062699/ https://www.ncbi.nlm.nih.gov/pubmed/35519817 http://dx.doi.org/10.3389/fpls.2022.873688 |
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