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Selective fetal termination for preeclampsia treatment in a dichorionic gestation with a triploid fetus: A case report

BACKGROUND: Triploidy is commonly associated with the development of early-onset preeclampsia. While previable preeclampsia is often a contraindication to prolonging pregnancy, there may be rare circumstances in which an alternative approach may be offered. CASE: A nulliparous patient with a dichori...

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Detalles Bibliográficos
Autores principales: Gulersen, Moti, Vohra, Nidhi, Bonanno, Clarissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062729/
https://www.ncbi.nlm.nih.gov/pubmed/35515706
http://dx.doi.org/10.1016/j.crwh.2022.e00415
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author Gulersen, Moti
Vohra, Nidhi
Bonanno, Clarissa
author_facet Gulersen, Moti
Vohra, Nidhi
Bonanno, Clarissa
author_sort Gulersen, Moti
collection PubMed
description BACKGROUND: Triploidy is commonly associated with the development of early-onset preeclampsia. While previable preeclampsia is often a contraindication to prolonging pregnancy, there may be rare circumstances in which an alternative approach may be offered. CASE: A nulliparous patient with a dichorionic twin gestation, recently diagnosed triploidy in one twin, and history of chronic hypertension presented at 18 weeks of gestation with signs and symptoms suggestive of preeclampsia. After symptomatic therapy and laboratory evaluations, selective fetal termination of the affected twin was elected and performed without complications. The patient subsequently delivered a healthy newborn at 37 weeks of gestation. CONCLUSION: Selective fetal termination may be considered a management option for previable preeclampsia in a dichorionic gestation with triploid fetus and was associated with a favorable outcome in this case.
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spelling pubmed-90627292022-05-04 Selective fetal termination for preeclampsia treatment in a dichorionic gestation with a triploid fetus: A case report Gulersen, Moti Vohra, Nidhi Bonanno, Clarissa Case Rep Womens Health Article BACKGROUND: Triploidy is commonly associated with the development of early-onset preeclampsia. While previable preeclampsia is often a contraindication to prolonging pregnancy, there may be rare circumstances in which an alternative approach may be offered. CASE: A nulliparous patient with a dichorionic twin gestation, recently diagnosed triploidy in one twin, and history of chronic hypertension presented at 18 weeks of gestation with signs and symptoms suggestive of preeclampsia. After symptomatic therapy and laboratory evaluations, selective fetal termination of the affected twin was elected and performed without complications. The patient subsequently delivered a healthy newborn at 37 weeks of gestation. CONCLUSION: Selective fetal termination may be considered a management option for previable preeclampsia in a dichorionic gestation with triploid fetus and was associated with a favorable outcome in this case. Elsevier 2022-04-25 /pmc/articles/PMC9062729/ /pubmed/35515706 http://dx.doi.org/10.1016/j.crwh.2022.e00415 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Gulersen, Moti
Vohra, Nidhi
Bonanno, Clarissa
Selective fetal termination for preeclampsia treatment in a dichorionic gestation with a triploid fetus: A case report
title Selective fetal termination for preeclampsia treatment in a dichorionic gestation with a triploid fetus: A case report
title_full Selective fetal termination for preeclampsia treatment in a dichorionic gestation with a triploid fetus: A case report
title_fullStr Selective fetal termination for preeclampsia treatment in a dichorionic gestation with a triploid fetus: A case report
title_full_unstemmed Selective fetal termination for preeclampsia treatment in a dichorionic gestation with a triploid fetus: A case report
title_short Selective fetal termination for preeclampsia treatment in a dichorionic gestation with a triploid fetus: A case report
title_sort selective fetal termination for preeclampsia treatment in a dichorionic gestation with a triploid fetus: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9062729/
https://www.ncbi.nlm.nih.gov/pubmed/35515706
http://dx.doi.org/10.1016/j.crwh.2022.e00415
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