Spinal deformity correction in ankylosing spondylitis

BACKGROUND: Ankylosing spondylitis (AS) is a complex, debilitating disease with few available medical therapies in its later stages. METHODS: We reviewed current clinical approaches for caring for AS patients with an emphasis on the risks and outcomes associated with surgical intervention. RESULTS: It is critical to understand the natural history and surgical outcomes of patient with AS. Surgery is not without risks, as a vertebral body osteotomy is often required to re-establish spinopelvic equilibrium. However, surgery can lead to clinical improvements in pain, disability, cardiac function, respiration, digestion, and sexual activity. CONCLUSION: Deformity correction for AS should be carefully considered in symptomatic patients.