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Synthesis of novel 10,11-methylenedioxy-camptothecin glycoside derivatives and investigation of their anti-tumor effects in vivo

10,11-Methylenedioxy-camptothecin (FL118) is a novel camptothecin analogue that possesses exceptional antitumor efficacy in human tumor xenograft models. The aim of the current study was to develop novel 20-substituted FL118 derivatives coupled with glycosyl-succinic acid esters with improved antitu...

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Detalles Bibliográficos
Autores principales:	Wu, Guanzhao, Mai, Xiaoyuan, Liu, Feng, Lin, Mingming, Dong, Xueyang, Xu, Qingliang, Hao, Cui, Zhang, Lijuan, Yu, Rilei, Jiang, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063016/ https://www.ncbi.nlm.nih.gov/pubmed/35520228 http://dx.doi.org/10.1039/c9ra00315k

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