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KnotAli: informed energy minimization through the use of evolutionary information

BACKGROUND: Improving the prediction of structures, especially those containing pseudoknots (structures with crossing base pairs) is an ongoing challenge. Homology-based methods utilize structural similarities within a family to predict the structure. However, their prediction is limited to the cons...

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Detalles Bibliográficos
Autores principales: Gray, Mateo, Chester, Sean, Jabbari, Hosna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063079/
https://www.ncbi.nlm.nih.gov/pubmed/35505276
http://dx.doi.org/10.1186/s12859-022-04673-3