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A Multi-Scale Computational Model of Levodopa-Induced Toxicity in Parkinson's Disease
Parkinson's disease (PD) is caused by the progressive loss of dopaminergic cells in substantia nigra pars compacta (SNc). The root cause of this cell loss in PD is still not decisively elucidated. A recent line of thinking has traced the cause of PD neurodegeneration to metabolic deficiency. Le...
Autores principales: | Muddapu, Vignayanandam Ravindernath-Jayashree, Vijayakumar, Karthik, Ramakrishnan, Keerthiga, Chakravarthy, V. Srinivasa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063169/ https://www.ncbi.nlm.nih.gov/pubmed/35516806 http://dx.doi.org/10.3389/fnins.2022.797127 |
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