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Nanozyme-natural enzymes cascade catalyze cholesterol consumption and reverse cancer multidrug resistance
Multidrug resistance is still a major obstacle to cancer treatment. The most studies are to inhibit the activity of the drug transporter P-glycoprotein (P-gp), but the effect is not ideal. Herein, a nanosystem was built based on cascade catalytic consumption of cholesterol. Cholesterol oxidase (natu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063293/ https://www.ncbi.nlm.nih.gov/pubmed/35501796 http://dx.doi.org/10.1186/s12951-022-01406-9 |