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Nanozyme-natural enzymes cascade catalyze cholesterol consumption and reverse cancer multidrug resistance

Multidrug resistance is still a major obstacle to cancer treatment. The most studies are to inhibit the activity of the drug transporter P-glycoprotein (P-gp), but the effect is not ideal. Herein, a nanosystem was built based on cascade catalytic consumption of cholesterol. Cholesterol oxidase (natu...

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Detalles Bibliográficos
Autores principales: Du, Bin, Zheng, Mei, Ma, Huizhen, Huang, Jingshu, Jiao, Qingqing, Bai, Yimeng, Zhao, Mengmeng, Zhou, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063293/
https://www.ncbi.nlm.nih.gov/pubmed/35501796
http://dx.doi.org/10.1186/s12951-022-01406-9

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