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Bone Marrow-Derived Stem Cell Factor Regulates Prostate Cancer-Induced Shifts in Pre-Metastatic Niche Composition

Skeletal metastasis is the leading cause of morbidity and mortality in prostate cancer, with 80% of advanced prostate cancer patients developing bone metastases. Before metastasis, bone remodeling occurs, stimulating pre-metastatic niche formation and bone turnover, and platelets govern this process...

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Detalles Bibliográficos
Autores principales: Foster, Brittni M., Shi, Lihong, Harris, Koran S., Patel, Chirayu, Surratt, Victoria E., Langsten, Kendall L., Kerr, Bethany A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063312/
https://www.ncbi.nlm.nih.gov/pubmed/35515124
http://dx.doi.org/10.3389/fonc.2022.855188