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Bone Marrow-Derived Stem Cell Factor Regulates Prostate Cancer-Induced Shifts in Pre-Metastatic Niche Composition
Skeletal metastasis is the leading cause of morbidity and mortality in prostate cancer, with 80% of advanced prostate cancer patients developing bone metastases. Before metastasis, bone remodeling occurs, stimulating pre-metastatic niche formation and bone turnover, and platelets govern this process...
Autores principales: | Foster, Brittni M., Shi, Lihong, Harris, Koran S., Patel, Chirayu, Surratt, Victoria E., Langsten, Kendall L., Kerr, Bethany A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063312/ https://www.ncbi.nlm.nih.gov/pubmed/35515124 http://dx.doi.org/10.3389/fonc.2022.855188 |
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