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FBXW7 and the Hallmarks of Cancer: Underlying Mechanisms and Prospective Strategies

FBXW7, a member of the F-box protein family within the ubiquitin–proteasome system, performs an indispensable role in orchestrating cellular processes through ubiquitination and degradation of its substrates, such as c-MYC, mTOR, MCL-1, Notch, and cyclin E. Mainly functioning as a tumor suppressor,...

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Detalles Bibliográficos
Autores principales:	Shen, Wenyue, Zhou, Quanwei, Peng, Chenxi, Li, Jiaheng, Yuan, Qizhi, Zhu, Hecheng, Zhao, Ming, Jiang, Xingjun, Liu, Weidong, Ren, Caiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063462/ https://www.ncbi.nlm.nih.gov/pubmed/35515121 http://dx.doi.org/10.3389/fonc.2022.880077

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