Sensitive detection of methylated DNA and methyltransferase activity based on the lighting up of FAM-labeled DNA quenched fluorescence by gold nanoparticles

DNA methylation of cytosine bases, which is catalyzed by methyltransferase enzymes, involve biochemical processes that contribute to gene expression and gene regulation in cells. Detection of abnormal patterns of both methylated DNA and methyltransferase enzyme activity at early stages could be cons...

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Detalles Bibliográficos
Autores principales: Karimi, Mohammad Ali, Dadmehr, Mehdi, Hosseini, Morteza, Korouzhdehi, Behnaz, Oroojalian, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063544/
https://www.ncbi.nlm.nih.gov/pubmed/35516994
http://dx.doi.org/10.1039/c9ra01564g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063544/
https://www.ncbi.nlm.nih.gov/pubmed/35516994
http://dx.doi.org/10.1039/c9ra01564g

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