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Adequate prediction for inhibitor affinity of Aβ(40) protofibril using the linear interaction energy method
The search for efficient inhibitors targeting Aβ oligomers and fibrils is an important issue in Alzheimer's disease treatment. As a consequence, an accurate and computationally cheap approach to estimate the binding affinity for many ligands interacting with Aβ peptides is very important. Here,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063661/ https://www.ncbi.nlm.nih.gov/pubmed/35515829 http://dx.doi.org/10.1039/c9ra01177c |