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Synthesis of poly-functionalized benzofurans via one-pot domino oxidation/[3+2] cyclization reactions of a hydroquinone ester and ynamides

Densely substituted amino-functionalized benzofurans were concisely accessed via the first one-pot domino oxidation/[3+2] cyclization of a hydroquinone ester and easily accessible ynamides under mild conditions in a short time. The complex benzofurans were able to be efficiently synthesized all from...

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Autores principales: Zhang, Dongxin, Man, Jingjing, Chen, Yan, Yin, Lei, Zhong, Junchao, Zhang, Qian-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063667/
https://www.ncbi.nlm.nih.gov/pubmed/35515817
http://dx.doi.org/10.1039/c9ra02144b
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author Zhang, Dongxin
Man, Jingjing
Chen, Yan
Yin, Lei
Zhong, Junchao
Zhang, Qian-Feng
author_facet Zhang, Dongxin
Man, Jingjing
Chen, Yan
Yin, Lei
Zhong, Junchao
Zhang, Qian-Feng
author_sort Zhang, Dongxin
collection PubMed
description Densely substituted amino-functionalized benzofurans were concisely accessed via the first one-pot domino oxidation/[3+2] cyclization of a hydroquinone ester and easily accessible ynamides under mild conditions in a short time. The complex benzofurans were able to be efficiently synthesized all from simple and inexpensive starting materials in two steps.
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spelling pubmed-90636672022-05-04 Synthesis of poly-functionalized benzofurans via one-pot domino oxidation/[3+2] cyclization reactions of a hydroquinone ester and ynamides Zhang, Dongxin Man, Jingjing Chen, Yan Yin, Lei Zhong, Junchao Zhang, Qian-Feng RSC Adv Chemistry Densely substituted amino-functionalized benzofurans were concisely accessed via the first one-pot domino oxidation/[3+2] cyclization of a hydroquinone ester and easily accessible ynamides under mild conditions in a short time. The complex benzofurans were able to be efficiently synthesized all from simple and inexpensive starting materials in two steps. The Royal Society of Chemistry 2019-04-25 /pmc/articles/PMC9063667/ /pubmed/35515817 http://dx.doi.org/10.1039/c9ra02144b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Zhang, Dongxin
Man, Jingjing
Chen, Yan
Yin, Lei
Zhong, Junchao
Zhang, Qian-Feng
Synthesis of poly-functionalized benzofurans via one-pot domino oxidation/[3+2] cyclization reactions of a hydroquinone ester and ynamides
title Synthesis of poly-functionalized benzofurans via one-pot domino oxidation/[3+2] cyclization reactions of a hydroquinone ester and ynamides
title_full Synthesis of poly-functionalized benzofurans via one-pot domino oxidation/[3+2] cyclization reactions of a hydroquinone ester and ynamides
title_fullStr Synthesis of poly-functionalized benzofurans via one-pot domino oxidation/[3+2] cyclization reactions of a hydroquinone ester and ynamides
title_full_unstemmed Synthesis of poly-functionalized benzofurans via one-pot domino oxidation/[3+2] cyclization reactions of a hydroquinone ester and ynamides
title_short Synthesis of poly-functionalized benzofurans via one-pot domino oxidation/[3+2] cyclization reactions of a hydroquinone ester and ynamides
title_sort synthesis of poly-functionalized benzofurans via one-pot domino oxidation/[3+2] cyclization reactions of a hydroquinone ester and ynamides
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063667/
https://www.ncbi.nlm.nih.gov/pubmed/35515817
http://dx.doi.org/10.1039/c9ra02144b
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