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Diversification of circulating and tumor‐infiltrating plasmacytoid DCs towards the P3 (CD80(+) PDL1(−))‐pDC subset negatively correlated with clinical outcomes in melanoma patients

OBJECTIVES: Plasmacytoid DCs (pDCs) play a critical yet enigmatic role in antitumor immunity through their pleiotropic immunomodulatory functions. Despite proof of pDC diversity in several physiological or pathological contexts, pDCs have been studied as a whole population so far in cancer. The asse...

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Detalles Bibliográficos
Autores principales: Sosa Cuevas, Eleonora, Bendriss‐Vermare, Nathalie, Mouret, Stephane, De Fraipont, Florence, Charles, Julie, Valladeau‐Guilemond, Jenny, Chaperot, Laurence, Aspord, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063720/
https://www.ncbi.nlm.nih.gov/pubmed/35517992
http://dx.doi.org/10.1002/cti2.1382