Copper-catalyzed synthesis of 2-aminopyridylbenzoxazoles via domino reactions of intermolecular N-arylation and intramolecular O-arylation

A simple and general approach to nitrogen-containing heterocycles via copper-catalyzed domino reaction has been developed, and the corresponding 2-aminopyridylbenzoxazole derivatives were obtained in good to excellent yields using the readily available starting materials. This method possesses uniqu...

Descripción completa

Detalles Bibliográficos
Autor principal: Lu, Ju-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063911/
https://www.ncbi.nlm.nih.gov/pubmed/35519581
http://dx.doi.org/10.1039/c9ra01908a
_version_ 1784699253954707456
author Lu, Ju-You
author_facet Lu, Ju-You
author_sort Lu, Ju-You
collection PubMed
description A simple and general approach to nitrogen-containing heterocycles via copper-catalyzed domino reaction has been developed, and the corresponding 2-aminopyridylbenzoxazole derivatives were obtained in good to excellent yields using the readily available starting materials. This method possesses unique step economy features, and is of high tolerance towards various functional groups in the substrates.
format Online
Article
Text
id pubmed-9063911
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90639112022-05-04 Copper-catalyzed synthesis of 2-aminopyridylbenzoxazoles via domino reactions of intermolecular N-arylation and intramolecular O-arylation Lu, Ju-You RSC Adv Chemistry A simple and general approach to nitrogen-containing heterocycles via copper-catalyzed domino reaction has been developed, and the corresponding 2-aminopyridylbenzoxazole derivatives were obtained in good to excellent yields using the readily available starting materials. This method possesses unique step economy features, and is of high tolerance towards various functional groups in the substrates. The Royal Society of Chemistry 2019-05-01 /pmc/articles/PMC9063911/ /pubmed/35519581 http://dx.doi.org/10.1039/c9ra01908a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Lu, Ju-You
Copper-catalyzed synthesis of 2-aminopyridylbenzoxazoles via domino reactions of intermolecular N-arylation and intramolecular O-arylation
title Copper-catalyzed synthesis of 2-aminopyridylbenzoxazoles via domino reactions of intermolecular N-arylation and intramolecular O-arylation
title_full Copper-catalyzed synthesis of 2-aminopyridylbenzoxazoles via domino reactions of intermolecular N-arylation and intramolecular O-arylation
title_fullStr Copper-catalyzed synthesis of 2-aminopyridylbenzoxazoles via domino reactions of intermolecular N-arylation and intramolecular O-arylation
title_full_unstemmed Copper-catalyzed synthesis of 2-aminopyridylbenzoxazoles via domino reactions of intermolecular N-arylation and intramolecular O-arylation
title_short Copper-catalyzed synthesis of 2-aminopyridylbenzoxazoles via domino reactions of intermolecular N-arylation and intramolecular O-arylation
title_sort copper-catalyzed synthesis of 2-aminopyridylbenzoxazoles via domino reactions of intermolecular n-arylation and intramolecular o-arylation
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063911/
https://www.ncbi.nlm.nih.gov/pubmed/35519581
http://dx.doi.org/10.1039/c9ra01908a
work_keys_str_mv AT lujuyou coppercatalyzedsynthesisof2aminopyridylbenzoxazolesviadominoreactionsofintermolecularnarylationandintramolecularoarylation

Ejemplares similares