Cargando…
Critical role for the lung endothelial nonmuscle myosin light‐chain kinase isoform in the severity of inflammatory murine lung injury
Global knockout of the nonmuscle isoform of myosin light‐chain kinase (nmMLCK), a primary cellular regulator of cytoskeletal machinery, is strongly protective in preclinical murine models of inflammatory lung injury. The current study was designed to assess the specific contribution of endothelial c...
Autores principales: | Kempf, Carrie L., Sammani, Saad, Bermudez, Tadeo, Song, Jin H., Hernon, Vivian Reyes, Hufford, Matthew K., Burt, Jessica, Camp, Sara M., Dudek, Steven M., Garcia, Joe G. N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063969/ https://www.ncbi.nlm.nih.gov/pubmed/35514774 http://dx.doi.org/10.1002/pul2.12061 |
Ejemplares similares
-
Genetic and epigenetic regulation of the non-muscle myosin light chain kinase isoform by lung inflammatory factors and mechanical stress
por: Sun, Xiaoguang, et al.
Publicado: (2021) -
eNAMPT Neutralization Preserves Lung Fluid Balance and Reduces Acute Renal Injury in Porcine Sepsis/VILI-Induced Inflammatory Lung Injury
por: Sammani, Saad, et al.
Publicado: (2022) -
The impact of intravenous dodecafluoropentane on a murine model of acute lung injury
por: Mosier, Jarrod M., et al.
Publicado: (2023) -
eNAMPT neutralization reduces preclinical ARDS severity via rectified NFkB and Akt/mTORC2 signaling
por: Bermudez, Tadeo, et al.
Publicado: (2022) -
Nonmuscle myosin II isoforms interact with sodium channel alpha subunits
por: Dash, Bhagirathi, et al.
Publicado: (2018)