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Unique stabilizing mechanism provided by biocompatible choline-based ionic liquids for inhibiting dissociation of inactivated foot-and-mouth disease virus particles
Inactivated virus and virus-like particles (VLPs) are important classes of biopharmaceuticals for vaccines, immunotherapy and oncotherapy. Their complex particle structures are easily denatured during processing and storage, leading to loss in their biofunctionality. Ionic liquids (ILs) as stabilizi...
Autores principales: | Lin, Xuan, Yang, Yanli, Li, Shuai, Song, Yanmin, Ma, Guanghui, Su, Zhiguo, Zhang, Songping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063997/ https://www.ncbi.nlm.nih.gov/pubmed/35519561 http://dx.doi.org/10.1039/c9ra02722j |
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