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Screening of Organophosphate Flame Retardants with Placentation-Disrupting Effects in Human Trophoblast Organoid Model and Characterization of Adverse Pregnancy Outcomes in Mice

BACKGROUND: Abnormal placental development may result in adverse pregnancy outcomes and metabolic diseases in adulthood; however, it remains unknown whether and how xenobiotics affect human placentation. OBJECTIVES: This study aimed to screen and identify placentation-disrupting chemicals in commonl...

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Detalles Bibliográficos
Autores principales: Xu, Chenke, Ma, Haojia, Gao, Fumei, Zhang, Chenhao, Hu, Wenxin, Jia, Yingting, Xu, Jun, Hu, Jianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064024/
https://www.ncbi.nlm.nih.gov/pubmed/35503735
http://dx.doi.org/10.1289/EHP10273