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Inhibition of metal-induced amyloid β-peptide aggregation by a blood–brain barrier permeable silica–cyclen nanochelator

Alzheimer's disease (AD) is a neurodegenerative malady associated with amyloid β-peptide (Aβ) aggregation in the brain. Metal ions play important roles in Aβ aggregation and neurotoxicity. Metal chelators are potential therapeutic agents for AD because they could sequester metal ions from the A...

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Detalles Bibliográficos
Autores principales:	Wang, Jinzhuan, Wang, Kun, Zhu, Zhenzhu, He, Yafeng, Zhang, Changli, Guo, Zijian, Wang, Xiaoyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064035/ https://www.ncbi.nlm.nih.gov/pubmed/35519314 http://dx.doi.org/10.1039/c9ra02358e

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