Cargando…
Protein interactions with metallothionein-3 promote vectorial active transport in human proximal tubular cells
Metallothionein 3 (MT-3) is a small, cysteine-rich protein that binds to essential metals required for homeostasis, as well as to heavy metals that have the potential to exert toxic effects on cells. MT-3 is expressed by epithelial cells of the human kidney, including the cells of the proximal tubul...
Autores principales: | Kalyan, Gazal, Slusser-Nore, Andrea, Dunlevy, Jane R., Bathula, Chandra S., Shabb, John B., Muhonen, Wallace, Somji, Seema, Sens, Donald A., Garrett, Scott H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064079/ https://www.ncbi.nlm.nih.gov/pubmed/35503771 http://dx.doi.org/10.1371/journal.pone.0267599 |
Ejemplares similares
-
Cadherin Expression, Vectorial Active Transport, and Metallothionein Isoform 3 Mediated EMT/MET Responses in Cultured Primary and Immortalized Human Proximal Tubule Cells
por: Slusser, Andrea, et al.
Publicado: (2015) -
The unique C- and N-terminal sequences of Metallothionein isoform 3 mediate growth inhibition and Vectorial active transport in MCF-7 cells
por: Voels, Brent, et al.
Publicado: (2017) -
Loss of N-Cadherin Expression in Tumor Transplants Produced From As(+3)- and Cd(+2)-Transformed Human Urothelial (UROtsa) Cell Lines
por: Sandquist, Elizabeth J., et al.
Publicado: (2016) -
SPARC Expression Is Selectively Suppressed in Tumor Initiating Urospheres Isolated from As(+3)- and Cd(+2)-Transformed Human Urothelial Cells (UROtsa) Stably Transfected with SPARC
por: Slusser-Nore, Andrea, et al.
Publicado: (2016) -
Exposure of human proximal tubule cells to cd2+, zn2+, and Cu2+ induces metallothionein protein accumulation but not metallothionein isoform 2 mRNA.
por: Garrett, S H, et al.
Publicado: (1998)