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The effects of antibiotic cycling and mixing on acquisition of antibiotic resistant bacteria in the ICU: A post-hoc individual patient analysis of a prospective cluster-randomized crossover study

BACKGROUND: Repeated rotation of empiric antibiotic treatment strategies is hypothesized to reduce antibiotic resistance. Clinical rotation studies failed to change unit-wide prevalence of antibiotic resistant bacteria (ARB) carriage, including an international cluster-randomized crossover study. Un...

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Detalles Bibliográficos
Autores principales:	van Duijn, Pleun J., Verbrugghe, Walter, Jorens, Philippe G., Spöhr, Fabian, Schedler, Dirk, Deja, Maria, Rothbart, Andreas, Annane, Djillali, Lawrence, Christine, Jereb, Matjaz, Seme, Katja, Šifrer, Franc, Tomič, Viktorija, Estevez, Francisco, Carneiro, Jandira, Harbarth, Stephan, Bonten, Marc J. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064081/ https://www.ncbi.nlm.nih.gov/pubmed/35503768 http://dx.doi.org/10.1371/journal.pone.0265720

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