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Inhibition of G9a promoted 5-fluorouracil (5-FU) induced gastric cancer cell apoptosis via ROS/JNK signaling pathway in vitro and in vivo

A histone methyltransferase G9a, encoded by euchromatic histone-lysine N-methyltransferase 2 (EHMT2), is up-regulated in various cancers, and is involved in their poor prognosis. In the study reported here, the abnormal expression of G9a in gastric cancer it was investigated in vitro and in vivo. Fu...

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Detalles Bibliográficos
Autores principales:	Lou, Haizhou, Pan, Hongming, Huang, Zhijian, Wang, Zonglin, Wang, Dimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064134/ https://www.ncbi.nlm.nih.gov/pubmed/35516300 http://dx.doi.org/10.1039/c8ra10502b

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