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Single-molecule study on conformational dynamics of M.HhaI

We found that apo DNA methyltransferase M.HhaI under the physiological salt concentration does not possess the structure characterized by X-ray crystallography; instead, it interchanges between prefolded and unfolded states. Only after binding to the substrate, it transforms into a crystal-structure...

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Detalles Bibliográficos
Autores principales:	He, Shanshan, Yang, Chen, Peng, Sijia, Chen, Chunlai, Zhao, Xin Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064139/ https://www.ncbi.nlm.nih.gov/pubmed/35516350 http://dx.doi.org/10.1039/c9ra00021f

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