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Label-free cell phenotypic study of FFA4 and FFA1 and discovery of novel agonists of FFA4 from natural products

In this article, pharmacological studies of the free fatty acid receptor (FFA) 4 and FFA1 were conducted in transfected CHO cells (FFA4&FFA1) and HT29 cells with application of a label-free dynamic mass redistribution (DMR) assay. Commercially available compounds including α-linolenic acid (ALA)...

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Detalles Bibliográficos
Autores principales: Xu, Fangfang, Zhou, Han, Liu, Xiumei, Zhang, Xiuli, Wang, Zhiwei, Hou, Tao, Wang, Jixia, Qu, Lala, Zhang, Pengyu, Piao, Hailong, Liang, Xinmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064241/
https://www.ncbi.nlm.nih.gov/pubmed/35516320
http://dx.doi.org/10.1039/c9ra02142f