Cargando…
Label-free cell phenotypic study of FFA4 and FFA1 and discovery of novel agonists of FFA4 from natural products
In this article, pharmacological studies of the free fatty acid receptor (FFA) 4 and FFA1 were conducted in transfected CHO cells (FFA4&FFA1) and HT29 cells with application of a label-free dynamic mass redistribution (DMR) assay. Commercially available compounds including α-linolenic acid (ALA)...
Autores principales: | Xu, Fangfang, Zhou, Han, Liu, Xiumei, Zhang, Xiuli, Wang, Zhiwei, Hou, Tao, Wang, Jixia, Qu, Lala, Zhang, Pengyu, Piao, Hailong, Liang, Xinmiao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064241/ https://www.ncbi.nlm.nih.gov/pubmed/35516320 http://dx.doi.org/10.1039/c9ra02142f |
Ejemplares similares
-
Selective Orthosteric Free Fatty Acid Receptor 2 (FFA2) Agonists: IDENTIFICATION OF THE STRUCTURAL AND CHEMICAL REQUIREMENTS FOR SELECTIVE ACTIVATION OF FFA2 VERSUS FFA3
por: Schmidt, Johannes, et al.
Publicado: (2011) -
Long Chain Fatty Acids as Modulators of Immune Cells Function: Contribution of FFA1 and FFA4 Receptors
por: Hidalgo, Maria A., et al.
Publicado: (2021) -
OR23-4 Intestinal FFA2 and FFA3 Mediate Obesogenic Effects in Mice on a Western Diet
por: Gough, Sophie, et al.
Publicado: (2022) -
FFA4/GPR120: Pharmacology and Therapeutic Opportunities
por: Milligan, Graeme, et al.
Publicado: (2017) -
Pharmacological properties of acid N-thiazolylamide FFA2 agonists
por: Brown, Andrew J, et al.
Publicado: (2015)