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Measurements and simulations of microtubule growth imply strong longitudinal interactions and reveal a role for GDP on the elongating end

Microtubule polymerization dynamics result from the biochemical interactions of αβ-tubulin with the polymer end, but a quantitative understanding has been challenging to establish. We used interference reflection microscopy to make improved measurements of microtubule growth rates and growth fluctua...

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Detalles Bibliográficos
Autores principales:	Cleary, Joseph M, Kim, Tae, Cook, Annan SI, McCormick, Lauren A, Hancock, William O, Rice, Luke M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064298/ https://www.ncbi.nlm.nih.gov/pubmed/35420545 http://dx.doi.org/10.7554/eLife.75931

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