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The oncoprotein BCL6 enables solid tumor cells to evade genotoxic stress

Genotoxic agents remain the mainstay of cancer treatment. Unfortunately, the clinical benefits are often countered by a rapid tumor adaptive response. Here, we report that the oncoprotein B cell lymphoma 6 (BCL6) is a core component that confers solid tumor adaptive resistance to genotoxic stress. M...

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Detalles Bibliográficos
Autores principales: Liu, Yanan, Feng, Juanjuan, Yuan, Kun, Wu, Zhengzhen, Hu, Longmiao, Lu, Yue, Li, Kun, Guo, Jiawei, Chen, Jing, Ma, Chengbin, Pang, Xiufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064299/
https://www.ncbi.nlm.nih.gov/pubmed/35503721
http://dx.doi.org/10.7554/eLife.69255