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Identification of key transporters mediating uptake of aconitum alkaloids into the liver and kidneys and the potential mechanism of detoxification by active ingredients of liquorice

Aconite as a commonly used herb has been extensively applied in the treatment of rheumatoid arthritis, as pain relief, as well as for its cardiotonic actions. Aconitum alkaloids have been shown to be the most potent ingredients in aconite, in terms of efficacy against disease, but they are also high...

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Detalles Bibliográficos
Autores principales: He, Yufei, Wang, Ze, Wu, Weidang, Xie, Ying, Wei, Zihong, Yi, Xiulin, Zeng, Yong, Li, Yazhuo, Liu, Changxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064382/
https://www.ncbi.nlm.nih.gov/pubmed/35521419
http://dx.doi.org/10.1039/c9ra00393b