Transition-metal-free amination phosphoryl azide for the synthesis of phosphoramidates

A facile and efficient approach to phosphoramidates was developed via amination of phosphoryl azides. A variety of phosphoramidates were obtained in one step with good to excellent yields under a mild reaction system. The process uses easily available amines as a N source and offers a new opportunit...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Qing, Sun, Xiaohua, Yang, Xiaoqin, Wu, Minghu, Sun, Shaofa, Chen, Xiuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064390/
https://www.ncbi.nlm.nih.gov/pubmed/35521381
http://dx.doi.org/10.1039/c9ra03389k
_version_ 1784699365233786880
author Li, Qing
Sun, Xiaohua
Yang, Xiaoqin
Wu, Minghu
Sun, Shaofa
Chen, Xiuling
author_facet Li, Qing
Sun, Xiaohua
Yang, Xiaoqin
Wu, Minghu
Sun, Shaofa
Chen, Xiuling
author_sort Li, Qing
collection PubMed
description A facile and efficient approach to phosphoramidates was developed via amination of phosphoryl azides. A variety of phosphoramidates were obtained in one step with good to excellent yields under a mild reaction system. The process uses easily available amines as a N source and offers a new opportunity for P–N bond formation.
format Online
Article
Text
id pubmed-9064390
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90643902022-05-04 Transition-metal-free amination phosphoryl azide for the synthesis of phosphoramidates Li, Qing Sun, Xiaohua Yang, Xiaoqin Wu, Minghu Sun, Shaofa Chen, Xiuling RSC Adv Chemistry A facile and efficient approach to phosphoramidates was developed via amination of phosphoryl azides. A variety of phosphoramidates were obtained in one step with good to excellent yields under a mild reaction system. The process uses easily available amines as a N source and offers a new opportunity for P–N bond formation. The Royal Society of Chemistry 2019-05-22 /pmc/articles/PMC9064390/ /pubmed/35521381 http://dx.doi.org/10.1039/c9ra03389k Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Li, Qing
Sun, Xiaohua
Yang, Xiaoqin
Wu, Minghu
Sun, Shaofa
Chen, Xiuling
Transition-metal-free amination phosphoryl azide for the synthesis of phosphoramidates
title Transition-metal-free amination phosphoryl azide for the synthesis of phosphoramidates
title_full Transition-metal-free amination phosphoryl azide for the synthesis of phosphoramidates
title_fullStr Transition-metal-free amination phosphoryl azide for the synthesis of phosphoramidates
title_full_unstemmed Transition-metal-free amination phosphoryl azide for the synthesis of phosphoramidates
title_short Transition-metal-free amination phosphoryl azide for the synthesis of phosphoramidates
title_sort transition-metal-free amination phosphoryl azide for the synthesis of phosphoramidates
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064390/
https://www.ncbi.nlm.nih.gov/pubmed/35521381
http://dx.doi.org/10.1039/c9ra03389k
work_keys_str_mv AT liqing transitionmetalfreeaminationphosphorylazideforthesynthesisofphosphoramidates
AT sunxiaohua transitionmetalfreeaminationphosphorylazideforthesynthesisofphosphoramidates
AT yangxiaoqin transitionmetalfreeaminationphosphorylazideforthesynthesisofphosphoramidates
AT wuminghu transitionmetalfreeaminationphosphorylazideforthesynthesisofphosphoramidates
AT sunshaofa transitionmetalfreeaminationphosphorylazideforthesynthesisofphosphoramidates
AT chenxiuling transitionmetalfreeaminationphosphorylazideforthesynthesisofphosphoramidates

Ejemplares similares