Copper-catalyzed intramolecular cross dehydrogenative coupling approach to coumestans from 2′-hydroxyl-3-arylcoumarins

A copper-catalyzed intramolecular cross dehydrogenative C–O coupling reaction of 2′-hydroxyl-3-arylcoumarins was developed. This protocol provided a facile and efficient strategy for the construction of natural coumestans and derivatives in moderate to high yields. This transformation exhibited good...

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Detalles Bibliográficos
Autores principales: Song, Xianheng, Luo, Xiang, Sheng, Jianfei, Li, Jianheng, Zhu, Zefeng, Du, Zhibo, Miao, Hui, Yan, Meng, Li, Mingkang, Zou, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064580/
https://www.ncbi.nlm.nih.gov/pubmed/35519854
http://dx.doi.org/10.1039/c9ra01909j
Descripción
Sumario:A copper-catalyzed intramolecular cross dehydrogenative C–O coupling reaction of 2′-hydroxyl-3-arylcoumarins was developed. This protocol provided a facile and efficient strategy for the construction of natural coumestans and derivatives in moderate to high yields. This transformation exhibited good functional group compatibility and was amenable to substrates with free phenolic hydroxyl groups.

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