Clinical, radiological, and transbronchial biopsy findings in patients with long COVID-19: a case series

This brief communication demonstrates the correlation of persistent respiratory symptoms with functional, tomographic, and transbronchial pulmonary biopsy findings in patients with COVID-19 who had a long follow-up period. We report a series of six COVID-19 patients with pulmonary involvement who pr...

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Detalles Bibliográficos
Autores principales: Baldi, Bruno Guedes, Fabro, Alexandre Todorovic, Franco, Andreia Craveiro, Machado, Marília Helena C, Prudente, Robson Aparecido, Franco, Estefânia Thomé, Marrone, Sergio Ribeiro, do Vale, Simone Alves, Cezare, Talita Jacon, Moraes, Marcelo Padovani de Toledo, Ferreira, Eloara Vieira Machado, Albuquerque, André Luis Pereira, Sawamura, Marcio Valente Yamada, Tanni, Suzana Erico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Pneumologia e Tisiologia 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064656/
https://www.ncbi.nlm.nih.gov/pubmed/35508067
http://dx.doi.org/10.36416/1806-3756/e20210438
Descripción
Sumario:This brief communication demonstrates the correlation of persistent respiratory symptoms with functional, tomographic, and transbronchial pulmonary biopsy findings in patients with COVID-19 who had a long follow-up period. We report a series of six COVID-19 patients with pulmonary involvement who presented with persistent dyspnea within 4-15 months of discharge. We performed transbronchial biopsies, and the histopathological pattern consistently demonstrated peribronchial remodeling with interstitial pulmonary fibrosis. Therefore, lung biopsy may be useful in the approach of patients with long COVID-19, although the type of procedure, its precise indication, and the moment to perform it are yet to be clarified. (Brazilian Registry of Clinical Trials-ReBEC; identifier: RBR-8j9kqy [http://www.ensaiosclinicos.gov.br])

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