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Porcine hepatocytes culture on biofunctionalized 3D inverted colloidal crystal scaffolds as an in vitro model for predicting drug hepatotoxicity
As drug-induced hepatotoxicity represents one of the most common causes of drug failure, three-dimensional (3D) in vitro liver platforms represent a fantastic toolbox to predict drug toxicity and thus reduce in vivo animal studies and lessen drug attrition rates. The aim of this study is to establis...
Autores principales: | Wu, Lingyan, Ferracci, Gaia, Wang, Yan, Fan, Teng Fei, Cho, Nam-Joon, Chow, Pierce K. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064660/ https://www.ncbi.nlm.nih.gov/pubmed/35520590 http://dx.doi.org/10.1039/c9ra03225h |
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