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Novel dermacozine-1-carboxamides as promising anticancer agents with tubulin polymerization inhibitory activity

In the present study, novel dermacozine-1-carboxamides (8a–8n) were synthesized and screened for their in vitro cytotoxic activity against three different cancer cell lines: MCF-7 (breast cancer), A-549 (lung cancer) and DU145 (prostate cancer). All the compounds showed more efficiency against the D...

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Detalles Bibliográficos
Autores principales: Ghanta, Venkata Rao, Madala, Nagaraju, Pasula, Aparna, Pindiprolu, Sai Kiran S. S., Battula, Kumara Swamy, Krishnamurthy, Praveen T., Raman, Balamurali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064817/
https://www.ncbi.nlm.nih.gov/pubmed/35515253
http://dx.doi.org/10.1039/c9ra02416f