Cargando…

A reversible mitochondrial complex I thiol switch mediates hypoxic avoidance behavior in C. elegans

C. elegans react to metabolic distress caused by mismatches in oxygen and energy status via distinct behavioral responses. At the molecular level, these responses are coordinated by under-characterized, redox-sensitive processes, thought to initiate in mitochondria. Complex I of the electron transpo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Onukwufor, John O., Farooqi, M. Arsalan, Vodičková, Anežka, Koren, Shon A., Baldzizhar, Aksana, Berry, Brandon J., Beutner, Gisela, Porter, George A., Belousov, Vsevolod, Grossfield, Alan, Wojtovich, Andrew P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064984/ https://www.ncbi.nlm.nih.gov/pubmed/35504873 http://dx.doi.org/10.1038/s41467-022-30169-y

Ejemplares similares

Neuronal AMPK coordinates mitochondrial energy sensing and hypoxia resistance in C. elegans
por: Berry, Brandon J., et al.
Publicado: (2020)

Physiologic Implications of Reactive Oxygen Species Production by Mitochondrial Complex I Reverse Electron Transport
por: Onukwufor, John O., et al.
Publicado: (2019)

Iron Dysregulation in Mitochondrial Dysfunction and Alzheimer’s Disease
por: Onukwufor, John O., et al.
Publicado: (2022)

Mitochondrial complex I ROS production and redox signaling in hypoxia
por: Okoye, Chidozie N., et al.
Publicado: (2023)

All-optical spatiotemporal mapping of ROS dynamics across mitochondrial microdomains in situ
por: Koren, Shon A., et al.
Publicado: (2023)

Mos1 Element-Mediated CRISPR Integration of Transgenes in Caenorhabditis elegans
por: Philip, Nicholas S., et al.
Publicado: (2019)

Dietary thiols accelerate aging of C. elegans
por: Gusarov, Ivan, et al.
Publicado: (2021)

The glutathione system and the related thiol network in Caenorhabditis elegans
por: Ferguson, Gavin Douglas, et al.
Publicado: (2019)

Cyclophilin D, Somehow a Master Regulator of Mitochondrial Function
por: Porter, George A., et al.
Publicado: (2018)

Exploiting Thiol Modifications
por: Kiley, Patricia J, et al.
Publicado: (2004)

Reactive oxygen species drive foraging decisions in Caenorhabditis elegans
por: Bischer, Andrew P., et al.
Publicado: (2023)

Neonatal hypoxic ischemic encephalopathy increases acute kidney injury urinary biomarkers in a rat model
por: Groves, Angela M., et al.
Publicado: (2022)

Publisher Correction: Dietary thiols accelerate aging of C. elegans
por: Gusarov, Ivan, et al.
Publicado: (2021)

Initiation of Electron Transport Chain Activity in the Embryonic Heart Coincides with the Activation of Mitochondrial Complex 1 and the Formation of Supercomplexes
por: Beutner, Gisela, et al.
Publicado: (2014)

Cyclophilin D regulates the dynamic assembly of mitochondrial ATP synthase into synthasomes
por: Beutner, Gisela, et al.
Publicado: (2017)

microRNA regulation of the embryonic hypoxic response in Caenorhabditis elegans
por: Kagias, Konstantinos, et al.
Publicado: (2015)

Chromophore-Assisted Light Inactivation of Mitochondrial Electron Transport Chain Complex II in Caenorhabditis elegans
por: Wojtovich, Andrew P., et al.
Publicado: (2016)

Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents
por: Winter, Alan D., et al.
Publicado: (2022)

Effects of photobiomodulation and caffeine treatment on acute kidney injury in a hypoxic ischemic neonatal rat model
por: Groves, A. M., et al.
Publicado: (2023)

Mechanistic Insights into the Formation of Dodecanethiolate-Stabilized Magnetic Iridium Nanoparticles: Thiosulfate vs Thiol Ligands
por: Gavia, Diego J., et al.
Publicado: (2014)

A Pacemaker that was Avoided
por: Waseem, Husnain, et al.
Publicado: (2018)

Rapid and Thiol-Specific High-Throughput Assay for Simultaneous Relative Quantification of Total Thiols, Protein Thiols, and Nonprotein Thiols in Cells
por: Yang, Yang, et al.
Publicado: (2014)

Correction to “Mechanistic Insights into the Formation of Dodecanethiolate-Stabilized Magnetic Iridium Nanoparticles: Thiosulfate vs Thiol Ligands”
por: Gavia, Diego J., et al.
Publicado: (2014)

A proteomic view of Caenorhabditis elegans caused by short-term hypoxic stress
por: Li, Hualing, et al.
Publicado: (2010)

Transgenerational Diapause as an Avoidance Strategy against Bacterial Pathogens in Caenorhabditis elegans
por: Palominos, M. Fernanda, et al.
Publicado: (2017)

Protocol for transgenerational learned pathogen avoidance behavior assays in Caenorhabditis elegans
por: Moore, Rebecca S., et al.
Publicado: (2021)

Exercise and Mitochondrial Dynamics: Keeping in Shape with ROS and AMPK
por: Trewin, Adam J., et al.
Publicado: (2018)

Decreased Mitochondrial Membrane Potential Activates the Mitochondrial Unfolded Protein Response
por: Berry, Brandon J., et al.
Publicado: (2021)

Glucose-Induced Expression of DAPIT in Pancreatic β-Cells
por: Leguina-Ruzzi, Alberto, et al.
Publicado: (2020)

Trend to escape preoperative X-ray therapy with the aim to avoid concomitant COVID risks
por: Podpriatov, Sergii, et al.
Publicado: (2021)

Hypoxia and the Hypoxic Response Pathway Protect against Pore-Forming Toxins in C. elegans
por: Bellier, Audrey, et al.
Publicado: (2009)

Adaptation of leukemia cells to hypoxic condition through switching the energy metabolism or avoiding the oxidative stress
por: Goto, Mineaki, et al.
Publicado: (2014)

Neuronal and non-neuronal signals regulate Caernorhabditis elegans avoidance of contaminated food
por: Anderson, Alexandra, et al.
Publicado: (2018)

Caffeine-induced food-avoidance behavior is mediated by neuroendocrine signals in Caenorhabditis elegans
por: Min, Hyemin, et al.
Publicado: (2017)

Superoxide dismutase SOD-1 modulates C. elegans pathogen avoidance behavior
por: Horspool, Alexander M., et al.
Publicado: (2017)

C. elegans interprets bacterial non-coding RNAs to learn pathogenic avoidance
por: Kaletsky, Rachel, et al.
Publicado: (2020)

Investigations of thiol-modified phenol derivatives for the use in thiol–ene photopolymerizations
por: Reinelt, Sebastian, et al.
Publicado: (2014)

Thiol Quantification Using Colorimetric Thiol–Disulfide Exchange in Nonaqueous Solvents
por: Schmidt, Ryan, et al.
Publicado: (2023)

Antihyperglycaemic Effect of Tetracarpidium Conophorum Nuts in Alloxan Induced Diabetic Female Albino Rats
por: Onwuli, Donatus Onukwufor, et al.
Publicado: (2014)

Reaction of Chalcones with Cellular Thiols. The Effect of the 4-Substitution of Chalcones and Protonation State of the Thiols on the Addition Process. Diastereoselective Thiol Addition
por: Kenari, Fatemeh, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_q82ajivgnt93o5i3ec8g6fq90s