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Pantothenate kinase 2 interacts with PINK1 to regulate mitochondrial quality control via acetyl-CoA metabolism

Human neurodegenerative disorders often exhibit similar pathologies, suggesting a shared aetiology. Key pathological features of Parkinson’s disease (PD) are also observed in other neurodegenerative diseases. Pantothenate Kinase-Associated Neurodegeneration (PKAN) is caused by mutations in the human...

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Detalles Bibliográficos
Autores principales: Huang, Yunpeng, Wan, Zhihui, Tang, Yinglu, Xu, Junxuan, Laboret, Bretton, Nallamothu, Sree, Yang, Chenyu, Liu, Boxiang, Lu, Rongze Olivia, Lu, Bingwei, Feng, Juan, Cao, Jing, Hayflick, Susan, Wu, Zhihao, Zhou, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065001/
https://www.ncbi.nlm.nih.gov/pubmed/35504872
http://dx.doi.org/10.1038/s41467-022-30178-x