Correction of a chronic pulmonary disease through lentiviral vector-mediated protein expression

We developed a novel lentiviral vector, pseudotyped with the F and HN proteins from Sendai virus (rSIV.F/HN), that produces long-lasting, high-efficiency transduction of the respiratory epithelium. Here we addressed whether this platform technology can secrete sufficient levels of a therapeutic prot...

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Detalles Bibliográficos
Autores principales: Lund-Palau, Helena, Juarez-Molina, Claudia Ivette, Meng, Cuixiang, Bhargava, Anushka, Pilou, Aikaterini, Aziz, Kiran, Clarke, Nora, Atsumi, Naoko, Ashek, Ali, Wilson, Michael R., Takata, Masao, Padley, Simon, Gill, Deborah R., Hyde, Stephen C., Morgan, Cliff, Alton, Eric W.F.W., Griesenbach, Uta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065048/
https://www.ncbi.nlm.nih.gov/pubmed/35573048
http://dx.doi.org/10.1016/j.omtm.2022.04.002

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